Peptide Nasal Spray Supplies and Setup
A nasal spray takes four supplies: a metered pump bottle (usually 0.1 mL per press), bacteriostatic water or sterile 0.9% saline, a luer-lock syringe with a blunt needle to fill it, and a 0.22 µm filter for a bottle kept for weeks. Presses per bottle is bottle volume ÷ press volume: 10 mL at 0.1 mL is about 100, less the few used to prime it.
Last edited · written by PepPrep · not medical advice
Some peptides are commonly used as a nasal spray rather than an injection, and people search constantly for how to do it. This site does not tell you what to put in a spray or how much. It can tell you what the container needs to be, why the water matters, and where the measuring happens, because those are the parts that go wrong.
The four supplies
- A proper nasal spray bottle. A pharmacy-grade metered pump bottle gives the same amount every press, usually 0.1 mL. A dropper or a squeeze bottle does not, and "roughly the same" is the problem you are trying to avoid.
- Bacteriostatic water or sterile saline. Sterile 0.9% saline is gentler on the nose but has no preservative, so a saline-filled bottle is a days-not-weeks item; bac water keeps for about 28 days once opened. The water guide explains the difference.
- A syringe to transfer with. A luer-lock syringe and a blunt drawing needle; no sharp needle is needed anywhere in this process.
- A 0.22 µm syringe filter if you are filling a bottle that will be used for weeks. It removes bacteria from the liquid passing through it. It is not a substitute for a clean bottle, clean technique or preserved water, and it will not rescue something already contaminated.
Getting the numbers right
The only arithmetic is: how much is in the bottle, and how much comes out per press. Fill the bottle with a known volume (the syringe tells you), and the pump label tells you the volume per press. The reconstitution calculator does the maths for the vial; the press count is then the bottle's volume divided by the press volume. Write both on the bottle with a label: what, date, presses per bottle.
Keeping it clean
New bottle every fill. Do not top up an old one. Prime the pump into a tissue, not your nose. Wipe the nozzle after use and keep the cap on. Store it in the fridge between uses and let it come to room temperature for a few minutes before use; a cold spray stings. A bottle filled with bac water is a four-week item at most, because 28 days is how long its preservative is counted on once opened; saline has no preservative, so it is days, not weeks.
Two things that are not supplies problems
A burning or bitter spray is usually the liquid, not the bottle; saline is milder than bac water in the nose. And a spray that seems to do nothing is usually a pump that was not primed. Neither is fixed by a different bottle.
Supplies mentioned: Sprays & Droppers · Mixing & Water
Equipment only: nothing on this page is advice about what to inject, how much, or whether a product is fit to use. That comes from the product's labelling and whoever supplied it.